Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.44 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.44 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335568 | 0.86 | TTR (0.53) | TTRMCL1NFKB1KDM4EALDH1A1 | |
| SCHEMBL69226 | 0.81 | TTR (0.68) | TTRKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL30175920 | 0.81 | TTR (0.68) | TTRKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL17182478 | 0.79 | TTR (0.47) | TTRMCL1KDM4EALDH1A1HPGD | |
| SCHEMBL11332256 | 0.79 | CA12 (0.51) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL23693962 | 0.79 | TTR (0.57) | TTRKDM4EALDH1A1HPGDTHRB | |
| SCHEMBL17885121 | 0.76 | ALDH1A1 (0.63) | TTRMCL1KDM4EALDH1A1ALDH2 | |
| SCHEMBL10623602 | 0.76 | TTR (0.83) | TTRKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL11333196 | 0.75 | ALDH2 (0.49) | TTRMCL1NFKB1KDM4EALDH1A1 | |
| SCHEMBL11499651 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473304-B2 | Heterocyclic PAD4 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-11-18 | — | — | US | disclosed |
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-06-01 | — | — | US | disclosed |
| EP-4103559-A1 | HETEROCYCLIC PAD4 INHIBITORS | Bristol-Myers Squibb Company (US) | 2022-12-21 | — | — | EP | disclosed |
| WO-2021163254-A1 | HETEROCYCLIC PAD4 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-08-19 | — | — | WO | disclosed |
| CN-104592219-B | Compound, optical film and method for making optical film | 住友化学株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-103013206-B | Optics film composition and blooming | 住友化学株式会社 | 2016-12-07 | — | — | CN | disclosed |
| CN-104592219-A | Compound, optical film and method for making optical film | SUMITOMO CHEMICAL CO | 2015-05-06 | — | — | CN | disclosed |
| CN-101838264-B | Compound, optical film, and method for producing optical film | SUMITOMO CHEMICAL CO | 2014-12-03 | — | — | CN | disclosed |
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |
| CN-101838264-A | Compound, optical film, and method for producing optical film | SUMITOMO CHEMICAL CO | 2010-09-22 | — | — | CN | disclosed |
| CN-1051311-C | N-heteroaryl-n'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 2000-04-12 | — | — | CN | disclosed |
| US-4372970-A | NONPHYTOTOXIC, PHOTOSTABLE | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1983-02-08 | — | — | US | disclosed |
| WO-1981001408-A1 | SUBSTITUTED ACETIC ACID ESTERS AS PESTICIDES | SOREX LTD (GB) | 1981-05-28 | — | — | WO | disclosed |
| EP-0029360-A1 | Pesticidal compounds, compositions containing them and methods of killing arthropods using them | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-05-27 | — | — | EP | disclosed |
| US-4259338-A | Benzofuranyl-tetrahydropyridines and -piperidines, their acid addition salts and antidepressant preparations thereof | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| EP-0006524-A1 | Tetrahydropyridine and tetrahydropiperidine derivatives, their acid addition salts, processes for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473304-B2 | Heterocyclic PAD4 inhibitors | PADI6, PADI4, PADI1 | TTR 4535/4885MCL1 3851/4885NFKB1 2520/4885 |
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | PADI4, PADI2, PADI6 | TTR 3702/4885MCL1 3436/4885NFKB1 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.