Logran

SCHEMBL2369409

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	2/20	0.48

▸	KDM4E	B2RXH2	1/20	0.48

▸	NPC1	O15118	1/20	0.48

▸	MAPT	P10636	2/20	0.46

▸	SMN1; SMN2	Q16637	1/20	0.41

▸	GAA	P10253	1/20	0.39

▸	TP53	P04637	3/20	0.38

▸	KMT2A	Q03164	2/20	0.37

▸	CA12	O43570	1/20	0.37

▸	CA1	P00915	1/20	0.37

▸	CA2	P00918	1/20	0.37

▸	CA9	Q16790	1/20	0.37

▸	MEN1	O00255	1/20	0.36

▸	USP2	O75604	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Logran SCHEMBL24021	1.00	ALDH1A1 (0.48)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Logran SCHEMBL30116863	1.00	ALDH1A1 (0.48)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Logran SCHEMBL2370007	1.00	ALDH1A1 (0.48)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Logran SCHEMBL29351449	1.00	ALDH1A1 (0.48)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Logran SCHEMBL8535049	1.00	ALDH1A1 (0.48)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Logran SCHEMBL2369255	0.99	ALDH1A1 (0.47)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
SCHEMBL8378745	0.96	ALDH1A1 (0.48)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Logran SCHEMBL9066883	0.95	ALDH1A1 (0.55)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
SCHEMBL10915090	0.94	ALDH1A1 (0.51)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
SCHEMBL10383232	0.91	ALDH1A1 (0.46)	ALDH1A1KDM4ENPC1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011107741-A1	HERBICIDAL COMPOSITION COMPRISING A MIXTURE OF A FIRST HERBICIDE AND PINOXADEN	SYNGENTA PARTICIPATIONS AG (CH)	2011-09-09	—	—	WO	disclosed