Logran

Logran

SCHEMBL9066883

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2Cl)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
KDM4E B2RXH2 1/20 0.55
NPC1 O15118 1/20 0.55
MAPT P10636 1/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA9 Q16790 2/20 0.42
CA2 P00918 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
KMT2A Q03164 1/20 0.38
TP53 P04637 1/20 0.37
P2RY12 Q9H244 1/20 0.37
THRB P10828 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Logran SCHEMBL2369409 0.95 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTCA12
Logran SCHEMBL24021 0.95 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTCA12
Logran SCHEMBL30116863 0.95 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTCA12
Logran SCHEMBL29351449 0.95 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTCA12
Logran SCHEMBL8535049 0.95 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTCA12
Logran SCHEMBL2370007 0.95 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTCA12
Logran SCHEMBL2369255 0.94 ALDH1A1 (0.47) ALDH1A1KDM4ENPC1MAPTCA12
Chlorsulfuron SCHEMBL8632269 0.92 ALDH1A1 (0.54) ALDH1A1KDM4ENPC1MAPTCA12
SCHEMBL8378745 0.92 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTCA12
SCHEMBL10915090 0.90 ALDH1A1 (0.51) ALDH1A1KDM4ENPC1MAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996015667-A2 ANTIDOTE COMPOSITION AND METHOD FOR USE OF THE COMPOSITION Nitrokémia Rt. (HU) 1996-05-30 WO claimed