Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 4/20 | 0.42 |
| ▸ | ATP4B | P51164 | 4/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359338 | 0.76 | ESR1 (0.38) | MEN1KMT2AGAAESR1ALOX15 | |
| SCHEMBL6359795 | 0.73 | ALDH1A1 (0.42) | MEN1KMT2AGAAESR1ALOX15 | |
| SCHEMBL5790639 | 0.73 | HTT (0.35) | MEN1KMT2AGAAALOX15HSD17B10 | |
| SCHEMBL6364115 | 0.69 | HTT (0.41) | MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL6364382 | 0.66 | ESR1 (0.45) | GAAESR1HSD17B10GSK3AGSK3B | |
| SCHEMBL2368870 | 0.66 | LMNA (0.63) | MEN1KMT2AGAAHSD17B10GSK3A | |
| SCHEMBL3160306 | 0.66 | CYP19A1 (0.71) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL411704 | 0.64 | CYP19A1 (0.69) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL230077 | 0.64 | CYP19A1 (0.63) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL227437 | 0.64 | CYP19A1 (0.63) | CYP11B1CYP11B2CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022076-B2 | Thieno[2,3-d]pyrimidine derivatives as potassium channel modulators; antiarrhythmia agents | XENTION LIMITED (GB) | 2011-09-20 | — | — | US | disclosed |