Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23697626 | 0.90 | LMNA (0.59) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23697631 | 0.86 | KDM4E (0.54) | MAPTADAM17ADAMTS5ALDH1A1MEN1 | |
| SCHEMBL23697627 | 0.84 | MAPK1 (0.60) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23697634 | 0.81 | SMN1; SMN2 (0.61) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23697636 | 0.81 | HSD17B10 (0.60) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23697633 | 0.78 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23495318 | 0.77 | TP53 (0.69) | MAPTMMP2MMP13ADAM17ADAMTS5 | |
| SCHEMBL17504107 | 0.73 | MEN1 (0.55) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19851997 | 0.73 | DRD2 (0.50) | ALDH1A1MEN1KMT2A | |
| SCHEMBL17504163 | 0.72 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021149767-A1 | HETEROCYCLIC DERIVATIVE | 大日本住友製薬株式会社 | 2021-07-29 | — | — | WO | disclosed |