⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2370146 | 0.97 | NAAA (0.54) | — | |
| SCHEMBL2370192 | 0.92 | — | — | |
| SCHEMBL2370219 | 0.79 | — | — | |
| SCHEMBL68566 | 0.79 | CA12 (0.54) | — | |
| SCHEMBL12451150 | 0.79 | — | — | |
| SCHEMBL17333418 | 0.79 | — | — | |
| SCHEMBL11634700 | 0.77 | NAAA (0.61) | — | |
| SCHEMBL29165576 | 0.77 | NAAA (0.61) | — | |
| SCHEMBL29116596 | 0.77 | TSHR (0.55) | — | |
| SCHEMBL29165571 | 0.77 | NAAA (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180020662-A1 | Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | US | claimed |
| CN-107531635-A | Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-yl sulfonamides or salts thereof and their use for enhancing stress tolerance in plants | 拜耳作物科学股份公司 | 2018-01-02 | — | — | CN | claimed |
| EP-3256448-A1 | SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-12-20 | — | — | EP | claimed |
| WO-2016128365-A1 | SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-08-18 | — | — | WO | claimed |
| CN-102884054-B | Fluoroalkyl-substituted 2-amidobenzimidazoles and the use thereof for boosting stress tolerance in plants | BAYER IP GMBH | 2015-01-14 | — | — | CN | claimed |
| EP-2542533-B1 | FLUORALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THEIR USE FOR INCREASING STRESS TOLERANCE IN PLANTS | BAYER IP GMBH (DE) | 2014-09-10 | — | — | EP | claimed |
| EP-2561759-A1 | Fluoroalkyl-substituted 2-amidobenzimidazoles and their effect on plant growth | Bayer Cropscience AG (DE) | 2013-02-27 | — | — | EP | claimed |
| CN-102884054-A | Fluoroalkyl-substituted 2-amidobenzimidazoles and the use thereof for boosting stress tolerance in plants | BAYER IP GMBH | 2013-01-16 | — | — | CN | claimed |
| EP-2542533-A1 | FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS | Bayer Intellectual Property GmbH (DE) | 2013-01-09 | — | — | EP | claimed |
| WO-2011107504-A1 | FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2011-09-09 | — | — | WO | claimed |
| US-20110218103-A1 | Fluoroalkyl-substituted 2-amidobenzimidazoles | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | claimed |
| US-20180199575-A1 | SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | US | disclosed |
| EP-3322296-A1 | SUBSTITUTED OXO-TETRAHYDROQUINOLINYL-PHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-23 | — | — | EP | disclosed |
| CN-107846899-A | Substituted oxotetrahydroquinolylphosphinic amides and-phosphonamides or salts thereof and their use for increasing stress tolerance in plants | 拜耳农作物科学股份公司 | 2018-03-27 | — | — | CN | disclosed |
| US-20180020662-A1 | Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | US | disclosed |
| EP-2561759-A1 | Fluoroalkyl-substituted 2-amidobenzimidazoles and their effect on plant growth | Bayer Cropscience AG (DE) | 2013-02-27 | — | — | EP | disclosed |
| CN-102884054-A | Fluoroalkyl-substituted 2-amidobenzimidazoles and the use thereof for boosting stress tolerance in plants | BAYER IP GMBH | 2013-01-16 | — | — | CN | disclosed |
| EP-2542533-A1 | FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS | Bayer Intellectual Property GmbH (DE) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011107504-A1 | FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2011-09-09 | — | — | WO | disclosed |
| US-20110218103-A1 | Fluoroalkyl-substituted 2-amidobenzimidazoles | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |