SCHEMBL68566

SCHEMBL68566

CCCCCOC(F)=C(F)F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.54
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA9 Q16790 3/20 0.54
NAAA Q02083 1/20 0.46
EPHX1 P07099 1/20 0.43
TSHR P16473 3/20 0.42
LPAR2 Q9HBW0 3/20 0.41
LPAR3 Q9UBY5 3/20 0.41
ALDH1A1 P00352 1/20 0.41
HCAR2 Q8TDS4 2/20 0.41
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ESR1 P03372 1/20 0.39
AKR1C4 P17516 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6535312 0.92 ALDH1A1 (0.48) CA12CA1CA2CA9NAAA
SCHEMBL28407240 0.88 CA12 (0.44) CA12CA1CA2CA9NAAA
SCHEMBL2623205 0.80 ALDH1A1 (0.38) CA12CA1CA2CA9TSHR
Fluoride SCHEMBL27793234 0.79 HCAR2 (0.33) CA12CA1CA2CA9TSHR
SCHEMBL2369837 0.79
SCHEMBL10071487 0.78 ALDH1A1 (0.41) CA12CA1CA2CA9NAAA
SCHEMBL10071488 0.78 ALDH1A1 (0.41) CA12CA1CA2CA9NAAA
SCHEMBL29760513 0.78 CES2 (0.44) CA12CA1CA2CA9NAAA
SCHEMBL2370146 0.77 NAAA (0.54) CA12CA1CA2CA9NAAA
SCHEMBL29760655 0.76 CES2 (0.47) CA12CA1CA2CA9NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3561020-B1 REFRIGERANT COMPOSITION CONTAINING HYDROFLUOROOLEFIN ZHEJIANG QUHUA FLUOR CHEMISTRY CO LTD (CN) 2023-05-03 EP claimed
US-20210189207-A1 HYDROFLUOROOLEFINS-CONTAINING REFRIGERANT COMPOSITION ZHEJIANG QUHUA FLUOR-CHEMISTRY CO LTD (CN) 2021-06-24 US claimed
CN-107459652-B Heat-resistant silicone resin capable of being cured at room temperature and preparation method thereof 山东省科学院新材料研究所 2020-05-19 CN claimed
EP-3561020-A1 REFRIGERANT COMPOSITION CONTAINING HYDROFLUOROOLEFIN Zhejiang Quhua Fluor-Chemistry Co., Ltd. (CN) 2019-10-30 EP claimed
US-20070032628-A1 CROSSLINKED COMPOSITIONS COMPRISING A POLY(ARYLENE ETHER) AND A NONLINEAR OPTICAL CHROMOPHORE, AND DEVICES INCORPORATING SAME SILICON VALLEY BANK 2007-02-08 US claimed
US-7101957-B2 Crosslinked compositions comprising a poly(arylene ether) and a nonlinear optical chromophore, and devices incorporating same LUMERA CORPORATION (US) 2006-09-05 US claimed
US-7087701-B2 Poly(arylene ethers) with pendant crosslinkable groups, and devices incorporating same LUMERA CORPORATION (US) 2006-08-08 US claimed
US-7067593-B2 Poly(arylene ethers) with pendant crosslinkable groups, and devices incorporating same LUMERA CORPORATION (US) 2006-06-27 US claimed
US-7008556-B2 Process for preparing crosslinked polymer blends that include a luminescent polymer LUMERA CORPORATION (US) 2006-03-07 US claimed
US-7001678-B2 Crosslinked polymer blends that include a luminescent polymer, and devices incorporating same LUMERA CORPORATION (US) 2006-02-21 US claimed
US-20050239970-A1 Poly(arylene ethers) with pendant crosslinkable groups, and devices incorporating same LUMERA CORPORATION, A WASHINGTON CORPORATION 2005-10-27 US claimed
WO-2005049680-A2 POLY (ARYLENE ETHERS) WITH PENDANT CROSSLINKABLE GROUPS, DEVICES, AND COMPOSITIONS INCORPORATING SAME, AND PROCESSES FOR PREPARING SAME LUMERA CORPORATION (US) 2005-06-02 WO claimed
US-20050106416-A1 Process for preparing crosslinked polymer blends that include a luminescent polymer LUMERA CORPORATION 2005-05-19 US claimed
US-20050107567-A1 Poly(arylene ethers) with pendant crosslinkable groups, and devices incorporating same LUMERA CORPORATION 2005-05-19 US claimed
US-20050107569-A1 Crosslinked compositions comprising a poly(arylene ether) and a nonlinear optical chromophore, and devices incorporating same LUMERA CORPORATION 2005-05-19 US claimed
US-20050106417-A1 Crosslinked polymer blends that include a luminescent polymer, and devices incorporating same LUMERA CORPORATION 2005-05-19 US claimed
US-5364547-A Lubricants containing perfluorocyclobutane rings THE DOW CHEMICAL COMPANY (US) 1994-11-15 US claimed
WO-2024086390-A9 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO disclosed
WO-1994025547-A1 LUBRICANTS CONTAINING PERFLUOROCYCLOBUTANE RINGS THE DOW CHEMICAL COMPANY (US) 1994-11-10 WO disclosed
WO-1994025547-A1 LUBRICANTS CONTAINING PERFLUOROCYCLOBUTANE RINGS THE DOW CHEMICAL COMPANY (US) 1994-11-10 WO disclosed