Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24947165 | 0.87 | TDP1 (0.48) | HTTNPSR1HSP90AA1MAPTTDP1 | |
| SCHEMBL2847294 | 0.81 | TDP1 (0.64) | HTTNPSR1HSP90AA1MAPTTDP1 | |
| SCHEMBL9125892 | 0.80 | HTT (0.53) | HTTNPSR1HSP90AA1MAPTTDP1 | |
| SCHEMBL498071 | 0.79 | HTT (0.63) | HTTNPSR1HSP90AA1MAPTTDP1 | |
| SCHEMBL29547331 | 0.79 | XDH (0.43) | MAPTTDP1GAALMNACA12 | |
| SCHEMBL22906927 | 0.79 | XDH (0.43) | MAPTTDP1GAALMNACA12 | |
| SCHEMBL3078708 | 0.78 | MAPT (0.65) | HTTNPSR1HSP90AA1MAPTTDP1 | |
| SCHEMBL6043225 | 0.78 | HTT (0.61) | HTTNPSR1HSP90AA1MAPTTDP1 | |
| SCHEMBL136101 | 0.77 | MAPT (0.60) | HTTNPSR1HSP90AA1MAPTTDP1 | |
| SCHEMBL2374331 | 0.77 | HSP90AA1 (0.50) | HTTNPSR1HSP90AA1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970483-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-04-30 | — | — | US | disclosed |
| US-20210380565-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-12-09 | — | — | US | disclosed |
| EP-3858828-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970483-B2 | Heterocyclic compound | SLC10A2, VIP, HRH2 | HTT 1591/4885NPSR1 165/4885HSP90AA1 2237/4885 |
| US-20210380565-A1 | HETEROCYCLIC COMPOUND | SLC10A2, VIP, HRH2 | HTT 1591/4885NPSR1 165/4885HSP90AA1 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.