Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2507036 | 0.89 | TSHR (0.42) | TSHRNPSR1RXFP1SIRT2KMT2A | |
| SCHEMBL29354050 | 0.89 | TSHR (0.42) | TSHRNPSR1RXFP1SIRT2KMT2A | |
| Hydrochloric Acid SCHEMBL30943478 | 0.88 | TSHR (0.41) | TSHRNPSR1RXFP1SIRT2KMT2A | |
| SCHEMBL27808614 | 0.88 | TSHR (0.41) | TSHRNPSR1RXFP1SIRT2KMT2A | |
| Phosphine SCHEMBL28247442 | 0.88 | TSHR (0.41) | TSHRNPSR1RXFP1SIRT2KMT2A | |
| SCHEMBL29360593 | 0.84 | TSHR (0.46) | TSHRNPSR1RXFP1SIRT2KMT2A | |
| Fluoride Ion SCHEMBL17601912 | 0.83 | TSHR (0.45) | TSHRNPSR1RXFP1SIRT2KMT2A | |
| Succinchlorimide SCHEMBL27782733 | 0.81 | KMT2A (0.36) | TSHRNPSR1RXFP1SIRT2KMT2A | |
| SCHEMBL28555388 | 0.81 | TSHR (0.36) | TSHRNPSR1RXFP1SIRT2KMT2A | |
| SCHEMBL8623356 | 0.81 | TSHR (0.41) | TSHRNPSR1RXFP1SIRT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033436-A1 | DERIVATIVE OF SARSASAPOGENIN, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PHYTOVENT BIOPHARMA (CN) | 2022-02-03 | — | — | US | disclosed |
| EP-3858849-A1 | DERIVATIVE BASED ON COMMON ANEMARRHENAE RHIZOME SARSASAPOGENIN STRUCTURE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Phytovent Biopharma (CN) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033436-A1 | DERIVATIVE OF SARSASAPOGENIN, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SARS1, ACE2, FURIN | TSHR 4175/4885NPSR1 612/4885RXFP1 3912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.