Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2507036 | 0.91 | TSHR (0.42) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL29354050 | 0.91 | TSHR (0.42) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| Phosphine SCHEMBL28247442 | 0.89 | TSHR (0.41) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| Hydrochloric Acid SCHEMBL30943478 | 0.89 | TSHR (0.41) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL27808614 | 0.89 | TSHR (0.41) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL28432280 | 0.88 | SLC9A1 (0.45) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL1497619 | 0.88 | SLC9A1 (0.45) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL29352246 | 0.88 | SLC9A1 (0.45) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL29360593 | 0.85 | TSHR (0.46) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| Fluoride Ion SCHEMBL17601912 | 0.84 | TSHR (0.45) | TSHRNPSR1RXFP1SLC9A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149885-A | EBNA1 inhibitors and methods of using the same | 威斯塔解剖学和生物学研究所 | 2021-07-23 | — | — | CN | disclosed |
| CN-107848964-B | EBNA1 inhibitors and methods of using the same | 威斯塔解剖学和生物学研究所 | 2021-03-19 | — | — | CN | disclosed |