Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 17/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699266 | 1.00 | OPRM1 (0.44) | OPRM1OPRL1OPRK1 | |
| SCHEMBL23719008 | 0.78 | OPRM1 (0.46) | OPRM1OPRL1OPRK1 | |
| SCHEMBL23719065 | 0.78 | OPRM1 (0.52) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL23699329 | 0.77 | OPRM1 (0.45) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL23699330 | 0.77 | OPRM1 (0.45) | OPRM1OPRL1OPRK1 | |
| SCHEMBL23719114 | 0.77 | OPRL1 (0.46) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL23699302 | 0.77 | OPRM1 (0.51) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL23699445 | 0.76 | OPRL1 (0.45) | OPRM1OPRL1OPRK1 | |
| SCHEMBL23719096 | 0.75 | ME2 (0.54) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL23699282 | 0.74 | OPRM1 (0.47) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | claimed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |