Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334330 | 0.90 | MAPK8 (0.47) | MAPK1KDM4EGAAAOC3HDAC1 | |
| SCHEMBL22570292 | 0.90 | MAPK1 (0.46) | MAPK1KDM4EGAAAOC3HDAC1 | |
| SCHEMBL22570297 | 0.90 | GRM5 (0.49) | MAPK1KDM4EGAAAOC3HDAC1 | |
| SCHEMBL22570114 | 0.90 | MAPK8 (0.47) | MAPK1KDM4EGAAAOC3HDAC1 | |
| SCHEMBL25091274 | 0.86 | DRD2 (0.44) | MAPK1KDM4EGAAAOC3HDAC1 | |
| SCHEMBL24267578 | 0.86 | MAPK1 (0.42) | MAPK1KDM4EGAAAOC3HDAC1 | |
| SCHEMBL24267452 | 0.86 | DRD2 (0.44) | MAPK1KDM4EGAAAOC3HDAC1 | |
| SCHEMBL22570296 | 0.86 | MAPK1 (0.42) | MAPK1KDM4EGAAAOC3HDAC1 | |
| SCHEMBL24618831 | 0.86 | MAPK1 (0.42) | MAPK1KDM4EGAAAOC3HDAC1 | |
| SCHEMBL22570294 | 0.86 | MAPK1 (0.42) | MAPK1KDM4EGAAAOC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545042-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112191-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-09-15 | — | — | WO | disclosed |