Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 5/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.47 |
| ▸ | CDK7 | P50613 | 4/20 | 0.43 |
| ▸ | CDK9 | P50750 | 4/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22570114 | 1.00 | MAPK8 (0.47) | MAPK8MAPK10MAPK9MAPK14CDK7 | |
| SCHEMBL2370002 | 0.90 | MAPK1 (0.48) | MAPK8MAPK10MAPK9MAPK14MAPK1 | |
| SCHEMBL31038881 | 0.83 | MAPK1 (0.36) | MAPK8MAPK10MAPK9MAPK14CDK7 | |
| SCHEMBL22570292 | 0.81 | MAPK1 (0.46) | MAPK8MAPK1AOC3KDM4EGAA | |
| SCHEMBL22570297 | 0.81 | GRM5 (0.49) | MAPK8MAPK1AOC3KDM4EGAA | |
| SCHEMBL6508486 | 0.79 | KDM4E (0.64) | MAPK8MAPK10MAPK9MAPK14CDK7 | |
| SCHEMBL473432 | 0.79 | KDM4E (0.64) | MAPK8MAPK10MAPK9MAPK14CDK7 | |
| SCHEMBL15233041 | 0.79 | KDM4E (0.64) | MAPK8MAPK10MAPK9MAPK14CDK7 | |
| SCHEMBL24267578 | 0.77 | MAPK1 (0.42) | MAPK8MAPK10MAPK9MAPK1AOC3 | |
| SCHEMBL24267452 | 0.77 | DRD2 (0.44) | CDK7CDK9CCNKCSNK1A1CDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |