Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSH | P09668 | 1/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 9/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 6/20 | 0.49 |
| ▸ | CCKAR | P32238 | 1/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23700413 | 1.00 | PIN1 (0.53) | PIN1CTSLCTSSCTSKCTSH | |
| SCHEMBL23710313 | 1.00 | PIN1 (0.53) | PIN1CTSLCTSSCTSKCTSH | |
| SCHEMBL23700451 | 1.00 | PIN1 (0.53) | PIN1CTSLCTSSCTSKCTSH | |
| SCHEMBL23710086 | 0.93 | PIN1 (0.51) | PIN1CTSLCTSSCTSKCTSH | |
| SCHEMBL23710096 | 0.91 | CTSL (0.54) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL23700214 | 0.91 | CTSL (0.54) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL23700215 | 0.91 | CTSL (0.54) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL23700351 | 0.88 | CCKAR (0.53) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL23700356 | 0.88 | CCKAR (0.53) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL23700354 | 0.88 | CCKAR (0.53) | CTSLCTSSCTSKCTSHCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238225-A1 | PEPTIDOMIMETIC INHIBITORS OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE (PIN1) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238225-A1 | PEPTIDOMIMETIC INHIBITORS OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE (PIN1) | PIN1, PPIA, PPIE | PIN1 1/4885CTSL 882/4885CTSS 1613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.