SCHEMBL237013

SCHEMBL237013

O=C(c1cccs1)C(F)C(=O)C(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.51
CES1 P23141 2/20 0.51
KEAP1 Q14145 1/20 0.51
DAO P14920 1/20 0.48
RAB9A P51151 5/20 0.46
NPC1 O15118 4/20 0.46
LMNA P02545 4/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
POLB P06746 2/20 0.46
HDAC1 Q13547 1/20 0.46
TSHR P16473 2/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
HPGD P15428 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HPGDS O60760 1/20 0.43
GSK3B P49841 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9565989 0.98 CES2 (0.50) CES2CES1KEAP1DAORAB9A
SCHEMBL9566091 0.98 CES2 (0.50) CES2CES1KEAP1DAORAB9A
SCHEMBL10631243 0.98 CES2 (0.50) CES2CES1KEAP1DAORAB9A
Alcohol SCHEMBL27427458 0.92 TSHR (0.50) CES2CES1KEAP1DAORAB9A
SCHEMBL28843649 0.82 RAB9A (0.49) CES2CES1KEAP1DAORAB9A
SCHEMBL11208250 0.81 CES2 (0.51) CES2CES1KEAP1DAORAB9A
SCHEMBL28376224 0.79 TSHR (0.50) CES2CES1KEAP1DAORAB9A
SCHEMBL18810193 0.78 TSHR (0.50) CES2CES1KEAP1RAB9ANPC1
SCHEMBL7203380 0.75 RAB9A (0.55) CES2CES1KEAP1DAORAB9A
SCHEMBL26056789 0.74 CES2 (0.66) CES2CES1KEAP1DAORAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2393 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076969-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-03-19 US claimed
US-20260028685-A1 Saliva Stabilization Solution For Use In Nucleic Acid Amplification Reactions And Methods Of Use For The Detection Of Pathogen Nucleic Acids UNIV COLORADO REGENTS (US) 2026-01-29 US claimed
EP-4642921-A1 METHODS OF IDENTIFYING, IMAGING, AND CHARACTERIZING BACTERIAL SPORES USING LANTHANIDE-BETA-DIKETONES Temasek Life Sciences Laboratory Limited (SG) 2025-11-05 EP claimed
EP-4642865-A1 BACTERIAL SPORES AS GREEN AND EFFICIENT BIOLOGICAL-INORGANIC HYBRID PHOSPHORS Temasek Life Sciences Laboratory Limited (SG) 2025-11-05 EP claimed
US-12312520-B2 Rare earth oxide nanosheet composite modified by organic ligand, preparation method and OLED luminescent film Shanghai Alpha Lighting Equipment Testing Ltd. (SALT) (CN) 2025-05-27 US claimed
CN-119979152-A Preparation method and application of enrofloxacin ratio type fluorescent probe based on PQDs-LMOF 山东农业大学 2025-05-13 CN claimed
WO-2025085311-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF KMT2D-DEFICIENT CANCERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-24 WO claimed
CN-119771415-A Petal-shaped Co-Mg-Al-LDH, and preparation method and application thereof 河南农业大学 2025-04-08 CN claimed
CN-115724862-B Lead ion fluorescent probe and preparation and application methods thereof 浙江万里学院 2025-04-04 CN claimed
CN-118256718-B Alpha-diketo lithium ion extractant and extraction system 郑州天一萃取科技有限公司 2025-03-21 CN claimed
US-4488557-A Topical agent for transcutaneous measurement of partial pressure of oxygen ENGEL ROLF R 1984-12-18 US claimed
EP-0005859-B1 PROCESS FOR REDUCING METAL ION CONTENT OF AQUEOUS SOLUTIONS DE NORA PERMELEC S.P.A. (IT) 1983-02-16 EP claimed
US-4374120-A Fluorescence spectroscopy assay means with fluorescent chelate of a lanthanide WALLAC OY (FI) 1983-02-15 US claimed
EP-0055459-A1 Process for producing oxides using chemical vapour deposition Rikuun Electric co. (JP) 1982-07-07 EP claimed
US-4268539-A INDIUM NITRATE-DIKETONE REACTION PRODUCT TOKYO DENSHI KAGAKU KABUSHIKI KAISHA (JP) 1981-05-19 US claimed
US-4255319-A PHOSPHINE INHIBITION; NONTOXIC; STORAGE STABILITY; MATERIALS HANDLING UNION CARBIDE CORPORATION (US) 1981-03-10 US claimed
US-4225330-A Process for producing glass member SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1980-09-30 US claimed
US-4215009-A COMPLEXING ORONZIO DENORA IMPIANTI ELETTROCHIMICI S.P.A. (IT) 1980-07-29 US claimed
EP-0005859-A1 Process for reducing metal ion content of aqueous solutions DE NORA PERMELEC S.P.A. (IT) 1979-12-12 EP claimed
US-4051230-A POROUS MEMBRANE IMPREGNATED WITH ORGANIC CHELATING EXTRACTANT, REGENERATION OF CHELATING AGENT AND RELEASE OF METAL CATION BY ACID W. L. GORE & ASSOCIATES, INC. (US) 1977-09-27 US claimed