SCHEMBL23701634

SCHEMBL23701634

Cc1nccn1S(=O)(=O)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
RECQL P46063 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
POLB P06746 2/20 0.39
HTT P42858 1/20 0.39
KDM4E B2RXH2 2/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 4/20 0.38
RAB9A P51151 1/20 0.38
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
FDPS P14324 1/20 0.33
NR3C2 P08235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21034083 0.78 RECQL (0.44) KMT2ARECQLSMN1; SMN2POLBHTT
SCHEMBL8148844 0.77 RECQL (0.46) KMT2ARECQLSMN1; SMN2POLBHTT
SCHEMBL27700919 0.77 KMT2A (0.42) KMT2ARECQLSMN1; SMN2POLBHTT
SCHEMBL16508785 0.77 TSHR (0.47) KMT2ASMN1; SMN2TSHRALDH1A1CA12
SCHEMBL21493577 0.76 MCL1 (0.30)
SCHEMBL15041407 0.75 RECQL (0.45) KMT2ARECQLSMN1; SMN2POLBHTT
SCHEMBL5535962 0.75 ESR1 (0.42) KDM4EALDH1A1CA12CA1CA2
SCHEMBL28944437 0.74
Hydrochloric Acid SCHEMBL28623166 0.74
SCHEMBL28827551 0.74 RECQL (0.44) KMT2ARECQLSMN1; SMN2POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878466-A Trifluoro-azole and its preparation method 特里纳普克公司 2024-11-01 CN claimed
EP-4097089-A1 TRIFLAZOLES AND METHODS OF MAKING THE SAME Trinapco, Inc (US) 2022-12-07 EP claimed
CN-115038692-A Trifluozole and preparation method thereof 特里纳普克公司 2022-09-09 CN claimed
US-11242322-B2 Triflazoles and methods of making the same TRINAPCO, INC. (US) 2022-02-08 US claimed
WO-2021154345-A1 TRIFLAZOLES AND METHODS OF MAKING THE SAME TRINAPCO, INC. (US) 2021-08-05 WO claimed
US-20210238142-A1 TRIFLAZOLES AND METHODS OF MAKING THE SAME TRINAPCO, INC. (US) 2021-08-05 US claimed
US-20250289781-A1 TRIFLUOROMETHANESULFONYLATING AGENT COMPOSITION AND METHOD FOR PRODUCING TRIFLUOROMETHANESULFONYLOXY COMPOUND OR TRIFLUOROMETHANESULFONYL COMPOUND CENTRAL GLASS COMPANY, LIMITED (JP) 2025-09-18 US disclosed
CN-119137096-A Trifluoromethanesulfonyl a composition of the agent trifluoromethanesulfonyl oxy compounds or Process for producing trifluoromethanesulfonyl compound 中央硝子株式会社 2024-12-13 CN disclosed
CN-118878466-A Trifluoro-azole and its preparation method 特里纳普克公司 2024-11-01 CN disclosed
CN-115038692-B Trifluoro-azole and its preparation method 特里纳普克公司 2024-07-16 CN disclosed
WO-2023214552-A1 TRIFLUOROMETHANE SULFONYLATION AGENT COMPOSITION AND METHOD FOR PRODUCING TRIFLUOROMETHANESULFONYLOXY COMPOUND OR TRIFLUOROMETHANE SULFONYL COMPOUND セントラル硝子株式会社 2023-11-09 WO disclosed
WO-2023214552-A1 TRIFLUOROMETHANE SULFONYLATION AGENT COMPOSITION AND METHOD FOR PRODUCING TRIFLUOROMETHANESULFONYLOXY COMPOUND OR TRIFLUOROMETHANE SULFONYL COMPOUND セントラル硝子株式会社 2023-11-09 WO disclosed
EP-4097089-A1 TRIFLAZOLES AND METHODS OF MAKING THE SAME Trinapco, Inc (US) 2022-12-07 EP disclosed
CN-115038692-A Trifluozole and preparation method thereof 特里纳普克公司 2022-09-09 CN disclosed
US-11242322-B2 Triflazoles and methods of making the same TRINAPCO, INC. (US) 2022-02-08 US disclosed
WO-2021154345-A1 TRIFLAZOLES AND METHODS OF MAKING THE SAME TRINAPCO, INC. (US) 2021-08-05 WO disclosed
US-20210238142-A1 TRIFLAZOLES AND METHODS OF MAKING THE SAME TRINAPCO, INC. (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289781-A1 TRIFLUOROMETHANESULFONYLATING AGENT COMPOSITION AND METHOD FOR PRODUCING TRIFLUOROMETHANESULFONYLOXY COMPOUND OR TRIFLUOROMETHANESULFONYL COMPOUND AFF1, BRAF, AFF2 KMT2A 774/4885RECQL 3948/4885SMN1; SMN2 407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.