Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL22462539 | 0.94 | RECQL (0.41) | RECQLSMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL8148844 | 0.82 | RECQL (0.46) | RECQLSMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL15041407 | 0.80 | RECQL (0.45) | RECQLSMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL28827551 | 0.78 | RECQL (0.44) | RECQLSMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL28175124 | 0.78 | POLB (0.45) | RECQLSMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL27203361 | 0.78 | RECQL (0.44) | RECQLSMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL23701634 | 0.78 | KMT2A (0.41) | RECQLSMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL2053373 | 0.75 | KDM4E (0.45) | RECQLSMN1; SMN2POLBHTTKMT2A | |
| SCHEMBL28199523 | 0.74 | — | — | |
| SCHEMBL22462478 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715342-B1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHONGHONGXIN INVEST HOLDINGS SHENZHEN CO LTD (CN) | 2024-08-07 | — | — | EP | disclosed |
| CN-112105603-B | Sulfonyl diazoles and N- (fluorosulfonyl) oxazoles and methods of making the same | 特里纳普克公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11542236-B2 | Sulfonyldiazoles and N-(fluorosulfonyl)azoles, and methods of making the same | TRINAPCO, INC. (US) | 2023-01-03 | — | — | US | disclosed |
| CN-110589783-B | Preparation of FSO from fluorosulfonyl compound2N3In (1) | 中国科学院上海有机化学研究所 | 2022-07-19 | — | — | CN | disclosed |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-08-17 | — | — | US | disclosed |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-08-17 | — | — | US | disclosed |
| US-11046653-B2 | — | — | 2021-06-29 | — | — | US | disclosed |
| US-11046653-B2 | — | — | 2021-06-29 | — | — | US | disclosed |
| US-11014945-B2 | Sulfonyldiazoles and N-(fluorosulfonyl)azoles, and methods of making the same | TRINAPCO, INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20210009529-A1 | SULFONYLDIAZOLES AND N-(FLUOROSULFONYL)AZOLES, AND METHODS OF MAKING THE SAME | TRINAPCO, INC. (US) | 2021-01-14 | — | — | US | disclosed |
| CN-112105603-A | Sulfonyl diazoles and N- (fluorosulfonyl) azoles and methods for their preparation | 特里纳普克公司 | 2020-12-18 | — | — | CN | disclosed |
| US-20200369619-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2020-11-26 | — | — | US | disclosed |
| US-20200369619-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2020-11-26 | — | — | US | disclosed |
| US-20200317700-A1 | SULFONYLDIAZOLES AND N-(FLUOROSULFONYL)AZOLES, AND METHODS OF MAKING THE SAME | TRINAPCO, INC. (US) | 2020-10-08 | — | — | US | disclosed |
| EP-3715342-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2020-09-30 | — | — | EP | disclosed |
| EP-3715342-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2020-09-30 | — | — | EP | disclosed |
| CN-110590609-A | Fluorine-containing sulfonyl compound, intermediate, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2019-12-20 | — | — | CN | disclosed |
| CN-110589783-A | Preparation of FSO from fluorosulfonyl compound2N3In (1) | 中国科学院上海有机化学研究所 | 2019-12-20 | — | — | CN | disclosed |
| WO-2019101132-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海有机化学研究所 | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046653-B2 | — | CYP4F11, NOTUM, CYP2F1 | RECQL 2732/4885SMN1; SMN2 2893/4885POLB 3018/4885 |
| US-20200369619-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE1, NOTUM, WEE2 | RECQL 3363/4885SMN1; SMN2 3296/4885POLB 3906/4885 |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | WEE1, NOTUM, WEE2 | RECQL 3363/4885SMN1; SMN2 3296/4885POLB 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.