Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12320484 | 0.78 | ADORA2A (0.41) | ADORA2AADORA1PDPK1LOXL2ECE1 | |
| SCHEMBL12277372 | 0.74 | ADORA2A (0.43) | ADORA2AADORA1PDPK1LOXL2ECE1 | |
| SCHEMBL3777152 | 0.73 | ECE1 (0.46) | ADORA2AADORA1ALDH1A1PDPK1ECE1 | |
| SCHEMBL3838752 | 0.68 | ADORA2A (0.53) | ADORA2AADORA1ALDH1A1TSHRNOS1 | |
| SCHEMBL3663184 | 0.68 | ADORA2A (0.47) | ADORA2AADORA1ALDH1A1TSHRNOS1 | |
| SCHEMBL31631304 | 0.68 | ADORA2A (0.47) | ADORA2AADORA1ALDH1A1TSHRNOS1 | |
| SCHEMBL102331 | 0.67 | PDPK1 (0.59) | ADORA2AADORA1ALDH1A1TSHRNOS1 | |
| SCHEMBL5785414 | 0.67 | PDPK1 (0.37) | ADORA2AADORA1ALDH1A1TSHRNOS1 | |
| SCHEMBL5156992 | 0.67 | ADORA2A (0.47) | ADORA2AADORA1ALDH1A1TSHRNOS1 | |
| SCHEMBL20092688 | 0.65 | MGAM (0.42) | ADORA2AADORA1ALDH1A1HSP90AA1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210236466-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236466-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | ADORA2A 765/4885ADORA1 1295/4885ALDH1A1 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.