Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 8/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.37 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31140091 | 0.89 | KDM4E (0.56) | KDM4EBRD4BRDTBRD9BRD7 | |
| SCHEMBL23832881 | 0.89 | KDM4E (0.56) | KDM4EBRD4BRDTBRD9BRD7 | |
| SCHEMBL19682389 | 0.85 | BRD4 (0.40) | KDM4EBRD4DYRK1AHSD17B10BRDT | |
| SCHEMBL7103532 | 0.78 | BRD4 (0.43) | KDM4EBRD4DYRK1ABRDTBRD9 | |
| SCHEMBL31104321 | 0.78 | BRD4 (0.40) | KDM4EBRD4DYRK1ABRDTBRD9 | |
| SCHEMBL6686475 | 0.78 | BRD4 (0.42) | KDM4EBRD4DYRK1AHSD17B10BRDT | |
| SCHEMBL796568 | 0.76 | NISCH (0.38) | ALDH1A1LMNAMAPT | |
| SCHEMBL9457818 | 0.74 | KDM4E (0.81) | KDM4EBRD4ALDH1A1LMNAGAA | |
| SCHEMBL7410003 | 0.74 | ALDH1A1 (0.59) | KDM4EBRD4ALDH1A1LMNAGAA | |
| SCHEMBL9499775 | 0.73 | KDM4E (0.47) | KDM4EBRD4BRDTBRD9BRD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011107494-A1 | NOVEL AROMATIC GLYCOSIDE DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND THE USE THEREOF | SANOFI (FR) | 2011-09-09 | — | — | WO | disclosed |