Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.37 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430376 | 0.89 | PTGS1 (0.37) | BRD4KDM4EGAABRDTBRD9 | |
| SCHEMBL24542960 | 0.85 | BRD4 (0.42) | BRD4KDM4ELMNAGAADYRK1A | |
| SCHEMBL1477849 | 0.84 | ALDH1A1 (0.41) | BRD4KDM4ELMNAGAAALDH1A1 | |
| SCHEMBL29525031 | 0.84 | ALDH1A1 (0.41) | BRD4KDM4ELMNAGAAALDH1A1 | |
| SCHEMBL8237233 | 0.80 | ALDH1A1 (0.41) | BRD4BRDTBRD9BRD7CREBBP | |
| SCHEMBL2370165 | 0.78 | KDM4E (0.45) | BRD4KDM4ELMNAGAADYRK1A | |
| SCHEMBL19584901 | 0.78 | KDM4E (0.38) | BRD4KDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL31104321 | 0.78 | BRD4 (0.40) | BRD4KDM4ELMNAGAADYRK1A | |
| SCHEMBL23027524 | 0.78 | BRD4 (0.40) | BRD4CREBBPALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7103532 | 0.78 | BRD4 (0.43) | BRD4KDM4ELMNAGAADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071389-A2 | NON-STEROIDAL INFALMMATION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |