SCHEMBL23703360

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23703358	1.00	IDH2 (0.45)	IDH2KCNH2PRKCIPIK3CAIDH1
	SCHEMBL3321777	0.91	MAPK1 (0.46)	IDH2KCNH2PIK3CAIDH1MAPK1
	SCHEMBL25140729	0.79	KCNH2 (0.52)	IDH2KCNH2PRKCIPIK3CACHEK1
	SCHEMBL26775804	0.78	PRKCI (0.44)	PRKCIMAPK1
	SCHEMBL13326581	0.78	PRKCI (0.44)	PRKCIMAPK1
	SCHEMBL30478386	0.72	PIK3CA (0.49)	IDH2KCNH2PIK3CACHEK1CHEK2
	SCHEMBL13334977	0.71	BAZ2A (0.43)	KCNH2CHEK1MAPK1
	SCHEMBL12526259	0.70	IDH2 (0.50)	IDH2PIK3CAIDH1CHEK1MAPK1
	SCHEMBL22895360	0.70	PIK3CA (0.47)	IDH2PIK3CACHEK1MAPK1
	SCHEMBL974801	0.69	CHRM2 (0.44)	PRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.