Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | IDH2 | P48735 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30478179 | 0.76 | CHEK1 (0.43) | BRD4ATAD2BPTFCHEK1 | |
| SCHEMBL30478350 | 0.75 | PIK3CA (0.48) | PIK3CAIDH2BRD4ATAD2KCNH2 | |
| SCHEMBL12526259 | 0.74 | IDH2 (0.50) | PIK3CAIDH2CHEK1HRH4HRH3 | |
| SCHEMBL23703358 | 0.72 | IDH2 (0.45) | PIK3CAIDH2KCNH2HDAC4CHEK1 | |
| SCHEMBL23703360 | 0.72 | IDH2 (0.45) | PIK3CAIDH2KCNH2HDAC4CHEK1 | |
| Hydrochloric Acid SCHEMBL23360019 | 0.72 | HTR6 (0.47) | PIK3CAIDH2KCNH2CHEK1CHEK2 | |
| Hydrochloric Acid SCHEMBL23360017 | 0.72 | HTR6 (0.47) | PIK3CAIDH2KCNH2CHEK1CHEK2 | |
| SCHEMBL30478349 | 0.70 | HRH4 (0.38) | BRD4ATAD2KCNH2CHEK1HRH4 | |
| SCHEMBL27070117 | 0.70 | SFRP1 (0.53) | BRD4HDAC4 | |
| Hydrochloric Acid SCHEMBL22572981 | 0.70 | BPTF (0.43) | BRD4ATAD2KCNH2BPTFHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452984-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Molecure S.A. (PL) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023119233-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-06-29 | — | — | WO | disclosed |