Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30049375 | 0.85 | CA2 (0.54) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL18561465 | 0.81 | CA12 (0.42) | CA1CA2ALDH1A1MAPK1CA12 | |
| SCHEMBL23703097 | 0.81 | GAA (0.51) | CA1CA2ALDH1A1CYP3A4TSHR | |
| SCHEMBL8942619 | 0.80 | PSIP1 (0.50) | CA1CA2ACHEALDH1A1KDM4E | |
| SCHEMBL23703289 | 0.78 | CA2 (0.52) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL1542484 | 0.78 | CA1 (0.55) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL29667787 | 0.77 | CA2 (0.51) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL25118612 | 0.76 | CA1 (0.52) | CA1CA2ACHEALDH1A1HSD17B10 | |
| SCHEMBL19126866 | 0.76 | CA2 (0.59) | CA1CA2ACHEALDH1A1HSD17B10 | |
| SCHEMBL18342911 | 0.75 | F2 (0.49) | CA1CA2BCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097223-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-07 | — | — | EP | disclosed |
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |