Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993652 | 1.00 | GPR119 (0.46) | GPR119BRD3PRMT5IRAK4MEN1 | |
| SCHEMBL28864942 | 1.00 | GPR119 (0.46) | GPR119BRD3PRMT5IRAK4MEN1 | |
| SCHEMBL30078432 | 0.90 | GPR119 (0.52) | GPR119BRD3IRAK4MAPTALK | |
| SCHEMBL23704337 | 0.90 | GPR119 (0.52) | GPR119BRD3IRAK4MAPTALK | |
| SCHEMBL23704300 | 0.87 | PROKR1 (0.45) | KMT2APROKR1CYP11B1CYP11B2 | |
| SCHEMBL7897983 | 0.84 | MAPKAPK2 (0.53) | BRD3MEN1ALDH1A1KMT2APROKR1 | |
| SCHEMBL7893351 | 0.83 | PROKR1 (0.55) | GPR119BRD3PRMT5PROKR1HPGDS | |
| SCHEMBL23704175 | 0.77 | TLR9 (0.41) | MEN1KMT2AALK | |
| SCHEMBL2590004 | 0.75 | GPR119 (0.50) | GPR119IRAK4ALKHPGDSCHEK2 | |
| SCHEMBL31504833 | 0.74 | IRAK4 (0.46) | GPR119PRMT5IRAK4MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097084-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| WO-2021154902-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-08-05 | — | — | WO | disclosed |