Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.53 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993652 | 0.84 | GPR119 (0.46) | KMT2ABRD3PDE4BMEN1ALDH1A1 | |
| SCHEMBL23704259 | 0.84 | GPR119 (0.46) | KMT2ABRD3PDE4BMEN1ALDH1A1 | |
| SCHEMBL28864942 | 0.84 | GPR119 (0.46) | KMT2ABRD3PDE4BMEN1ALDH1A1 | |
| SCHEMBL7893351 | 0.84 | PROKR1 (0.55) | BRD3PROKR1 | |
| SCHEMBL18440796 | 0.82 | MTNR1A (0.76) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28782629 | 0.77 | PDE4B (0.54) | KMT2AMTNR1AMTNR1BPDE4BHTT | |
| SCHEMBL21359263 | 0.76 | BCL9 (0.60) | KMT2APDE4BMEN1ALDH1A1PROKR1 | |
| SCHEMBL7901095 | 0.75 | HPGDS (0.46) | BRD3PROKR1 | |
| SCHEMBL7892876 | 0.75 | STS (0.46) | KMT2AMEN1ALDH1A1PROKR1 | |
| SCHEMBL15649592 | 0.75 | PDE4B (0.54) | KMT2APDE4BHTTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |