Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17710274 | 0.82 | GRM5 (0.35) | GRM5NPC1RAB9ASMN1; SMN2GRIN2B | |
| SCHEMBL5742391 | 0.80 | GRM5 (0.43) | GRM5NPC1RAB9ASMN1; SMN2GRIN2B | |
| SCHEMBL2954219 | 0.78 | HSD11B1 (0.41) | KCNH2PARP1 | |
| SCHEMBL5236735 | 0.78 | KCNH2 (0.35) | GRM5GRIN2BHRH4KCNH2PARP1 | |
| SCHEMBL23015787 | 0.75 | PARP1 (0.44) | GRM5GRIN2BCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL45869 | 0.75 | KCNH2 (0.52) | GRIN2BHRH4KCNH2PARP1GRIN2D | |
| SCHEMBL7354283 | 0.73 | TRPV3 (0.39) | GRM5NPC1RAB9ASMN1; SMN2GRIN2B | |
| SCHEMBL4711258 | 0.73 | GRM5 (0.54) | GRM5TRPV3 | |
| SCHEMBL11564452 | 0.73 | KCNH2 (0.50) | GRIN2BHRH4KCNH2PARP1GRIN2D | |
| SCHEMBL23075939 | 0.72 | GRM5 (0.62) | GRM5NPC1RAB9ASMN1; SMN2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154902-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-08-05 | — | — | WO | disclosed |