Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2797523 | 0.98 | JAK3 (0.48) | HRH1JAK3CHRM3SLC6A2L3MBTL1 | |
| SCHEMBL17209394 | 0.84 | IRAK4 (0.54) | HRH1JAK3L3MBTL1RAB9ANPC1 | |
| SCHEMBL634124 | 0.78 | CYP1A2 (0.48) | LMNACYP1A2CYP2C19EGFRNCF1 | |
| SCHEMBL8482284 | 0.77 | L3MBTL1 (0.46) | JAK3L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL8482286 | 0.77 | L3MBTL1 (0.46) | JAK3L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL17209403 | 0.76 | IRAK4 (0.57) | HRH1JAK3L3MBTL1LMNACYP2C19 | |
| SCHEMBL8487015 | 0.76 | IRAK4 (0.43) | JAK3L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL5469724 | 0.76 | ROCK1 (0.49) | HRH1CHRM3SLC6A2NMT1IRAK4 | |
| SCHEMBL24089854 | 0.76 | AR (0.49) | HRH1SLC6A2NMT1ADRB2NCF1 | |
| Hydrochloric Acid SCHEMBL5476262 | 0.75 | ROCK1 (0.48) | HRH1CHRM3SLC6A2NMT1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858813-A1 | QUINOLONE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITED ACTIVITY | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |