SCHEMBL23707462

SCHEMBL23707462

CCOC(=O)C(C)N1CC(C)C(Oc2ccnc3ccc(F)cc23)C1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.49
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23707461 0.87 IDO1 (0.55) IDO1CYP3A4
SCHEMBL24089856 0.83 IDO1 (0.55) IDO1CYP3A4
SCHEMBL23707514 0.82 IDO1 (0.49) IDO1CYP3A4
SCHEMBL23707491 0.81 IDO1 (0.59) IDO1CYP3A4
SCHEMBL23707506 0.81 IDO1 (0.38) IDO1
SCHEMBL23699072 0.81 IDO1 (0.52) IDO1CYP3A4
SCHEMBL22270531 0.78 IDO1 (0.48) IDO1CYP3A4
SCHEMBL23699135 0.78 IDO1 (0.42) IDO1CYP3A4
SCHEMBL23699089 0.77 IDO1 (0.44) IDO1CYP3A4
SCHEMBL23699147 0.77 IDO1 (0.43) IDO1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858813-A1 QUINOLONE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITED ACTIVITY Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2021-08-04 EP disclosed