TAF15 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to TAF15 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load	PHASE1	COMPLETED
Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma	PHASE1	WITHDRAWN
Single-Dose AAV-MECP2 Safety/Tolerability and Efficacy in Rett Syndrome	EARLY_PHASE1	ACTIVE_NOT_RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Identification of New FTLD Genes	nan	UNKNOWN
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors	nan	COMPLETED
Amyotrophic Lateral Sclerosis (ALS) Families Project	nan	RECRUITING
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
Genetics of Recurrent Early Onset Major Depression	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Genomic Translation for Amyotrophic Lateral Sclerosis Care	nan	COMPLETED
Pathogenetic Basis of Aortopathy and Aortic Valve Disease	nan	ACTIVE_NOT_RECRUITING
Clinical Evaluation of Patients With X-linked Retinitis Pigmentosa (XLRP)	nan	COMPLETED
Imaging Genetics of Laryngeal Dystonia	nan	RECRUITING
Collection of Blood Samples for DNA in Motor Neuron Disease	nan	COMPLETED
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Gene Analysis of Parkinson's Disease	nan	COMPLETED
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm	nan	COMPLETED
Genetics of Familial and Sporadic ALS	nan	COMPLETED
Telomere and Telomerase	nan	WITHDRAWN
Familial Intracranial Aneurysm Study II	nan	COMPLETED
Genetic and Blood Biomarkers in Neurological and Neuromuscular Diseases	nan	COMPLETED
Bipolar Disorder With Alcoholism in Han Chinese	nan	UNKNOWN
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics	nan	COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a TAF15 binder may also engage these)

Protein	Name	Similarity
FUS	RNA-binding protein FUS	0.991	landscape →
Q27294	—	0.989	Q27294 →
Q28009	—	0.988	Q28009 →
P56959	—	0.988	P56959 →
Q94KD0	—	0.986	Q94KD0 →
HNRNPA3	Heterogeneous nuclear ribonucleoprotein A3	0.981	landscape →
Q5RBU8	—	0.981	Q5RBU8 →
A7VJC2	—	0.981	A7VJC2 →
P21522	—	0.980	P21522 →
Q8BG05	—	0.980	Q8BG05 →
Q6URK4	—	0.979	Q6URK4 →
P51992	—	0.979	P51992 →
P48810	—	0.978	P48810 →
P51968	—	0.977	P51968 →
P17130	—	0.977	P17130 →
HNRNPA1	Heterogeneous nuclear ribonucleoprotein A1	0.977	landscape →
A5A6M3	—	0.976	A5A6M3 →
P38159	—	0.976	P38159 →
Q22037	—	0.976	Q22037 →
Q61545	—	0.976	Q61545 →
P51990	—	0.975	P51990 →
Q7ZWA3	—	0.975	Q7ZWA3 →
P51989	—	0.975	P51989 →
Q9TTV2	—	0.975	Q9TTV2 →
Q9LIN3	—	0.975	Q9LIN3 →
EWSR1	RNA-binding protein EWS	0.975	landscape →
Q6IRQ4	—	0.974	Q6IRQ4 →
Q4R7F0	—	0.974	Q4R7F0 →
HNRNPA2B1	Heterogeneous nuclear ribonucleoproteins A2/B1	0.974	landscape →
Q9WV02	—	0.974	Q9WV02 →