Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449748 | 0.71 | KMT2A (0.66) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL19449736 | 0.69 | KMT2A (0.49) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL17560970 | 0.67 | KMT2A (0.44) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL17560967 | 0.67 | KMT2A (0.44) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL15965638 | 0.61 | KMT2A (0.60) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL17560842 | 0.59 | MEN1 (0.62) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL17560848 | 0.59 | MEN1 (0.62) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL15965635 | 0.57 | MAPT (0.60) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL15722733 | 0.56 | MPO (0.64) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL23996036 | 0.56 | KMT2A (0.51) | KMT2AMEN1GAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188722-B1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-08-04 | — | — | EP | disclosed |