Methacrylic Acid

Methacrylic Acid

SCHEMBL4296926

C=C(C)C(=O)O.C=C(C=C(C)C(=O)O)C(=O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
CYP2C9 P11712 1/20 0.32
PTGS1 P23219 1/20 0.32
AKR1C3 P42330 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15298996 0.95 PTGS1 (0.34) TDP1CYP2C9PTGS1AKR1C3MAPT
SCHEMBL137715 0.95 PTGS1 (0.34) TDP1CYP2C9PTGS1AKR1C3MAPT
SCHEMBL28861159 0.92 PTGS1 (0.33) CYP2C9PTGS1AKR1C3MAPT
Acrylic Acid SCHEMBL5423268 0.86 LMNA (0.46) CYP2C9PTGS1AKR1C3
SCHEMBL4947083 0.83 ALDH1A1 (0.58) CYP2C9
Methacrylic Acid SCHEMBL1443532 0.82 HTT (0.39) TDP1CYP2C9PTGS1AKR1C3MAPT
SCHEMBL22193118 0.81 CYP2C9 (0.34) CYP2C9PTGS1AKR1C3
Methacrylic Acid SCHEMBL8425141 0.80 TDP1 (0.33) TDP1CYP2C9PTGS1AKR1C3MAPT
SCHEMBL14020469 0.80
Methacrylic Acid SCHEMBL8425146 0.80 TDP1 (0.33) TDP1CYP2C9PTGS1AKR1C3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524768-B2 Antioxidants for preventing and treating diseases caused by oxidative stress GITLIN ISAAK GRIGORIEVICH (RU) 2013-09-03 US disclosed
US-20090170789-A1 Antioxidants for preventing and treating diseases caused by oxidative stress GITLIN ISAAK GRIGORIEVICH 2009-07-02 US disclosed
US-6828368-B2 Useful for the preparation of a heat-sensitive tacky adhesive having excellent adhesive strength and blocking resistance; solid plasticizer DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-07 US disclosed
EP-1298121-A1 BIS(CIS-3,3,5-TRIMETHYLCYCLOHEXYL) PHTHALATE, PROCESS FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION Daicel Chemical Industries, Ltd. (JP) 2003-04-02 EP disclosed
US-20020193482-A1 Bis(cis-3,3,5-trimethylcyclohexyl) phthalate, process for producing the same, and thermoplastic resin composition DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193482-A1 Bis(cis-3,3,5-trimethylcyclohexyl) phthalate, process for producing the same, and thermoplastic resin composition PSMA3, CDH1, DPY30 TDP1 2932/4885CYP2C9 671/4885PTGS1 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.