Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.43 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23700450 | 0.91 | DPP3 (0.52) | DPP3KISS1RTACR1 | |
| SCHEMBL23700448 | 0.91 | DPP3 (0.52) | DPP3KISS1RTACR1 | |
| SCHEMBL23710074 | 0.91 | DPP3 (0.52) | DPP3KISS1RTACR1 | |
| SCHEMBL23710249 | 0.84 | KISS1R (0.48) | DPP3KISS1RTACR1 | |
| SCHEMBL23700272 | 0.82 | DPP3 (0.53) | DPP3KISS1RTACR1 | |
| SCHEMBL23700273 | 0.82 | DPP3 (0.53) | DPP3KISS1RTACR1 | |
| SCHEMBL23700467 | 0.81 | DPP3 (0.52) | DPP3KISS1RTACR1 | |
| SCHEMBL23700466 | 0.81 | DPP3 (0.52) | DPP3KISS1RTACR1 | |
| SCHEMBL31599476 | 0.78 | KISS1R (0.54) | DPP3KISS1RTACR1 | |
| SCHEMBL30466184 | 0.77 | KISS1R (0.50) | DPP3KISS1RTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238225-A1 | PEPTIDOMIMETIC INHIBITORS OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE (PIN1) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238225-A1 | PEPTIDOMIMETIC INHIBITORS OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE (PIN1) | PIN1, PPIA, PPIE | DPP3 116/4885SSTR2 4219/4885KISS1R 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.