Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308998 | 0.92 | PAOX (0.60) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL4391001 | 0.89 | PAOX (0.52) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL14198854 | 0.89 | ALDH1A1 (0.59) | HIF1AKDM4EMAPK1PAOXALDH1A1 | |
| SCHEMBL24611784 | 0.89 | ALDH1A1 (0.59) | HIF1AKDM4EMAPK1PAOXALDH1A1 | |
| SCHEMBL16853212 | 0.86 | ALDH1A1 (0.55) | HIF1AKDM4EMAPK1PAOXALDH1A1 | |
| SCHEMBL13151210 | 0.84 | KDM4E (0.80) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL18059006 | 0.83 | PAOX (0.50) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL14739904 | 0.83 | KDM4E (1.00) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL6516953 | 0.83 | KDM4E (1.00) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL14740196 | 0.83 | KDM4E (1.00) | HIF1AKDM4EMAPK1PAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858385-A2 | POLYMER-CONJUGATED METAP2 INHIBITORS, AND THERAPEUTIC METHODS OF USE THEREOF | Syndevrx, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |