Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23710508 | 0.89 | HIF1A (0.70) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL3074874 | 0.87 | CA2 (0.44) | PAOXKDM4EALDH1A1CA1CA2 | |
| SCHEMBL12799430 | 0.82 | KDM4E (0.52) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL19308998 | 0.82 | PAOX (0.60) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL8107 | 0.81 | KDM4E (0.71) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL24894923 | 0.80 | CA2 (0.44) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL12655123 | 0.80 | — | — | |
| SCHEMBL18160754 | 0.79 | CA2 (0.40) | KDM4EALDH1A1CA1CA2MEN1 | |
| SCHEMBL17546697 | 0.78 | PAOX (0.61) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL10488313 | 0.77 | KDM4E (0.52) | PAOXKDM4EMAPK1HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963357-B1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | SALVAT LAB SA (ES) | 2009-12-09 | — | — | EP | disclosed |