Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22295960 | 0.90 | EPHX1 (0.52) | EPHX1NAAAFAAHCASP2PLA2G2A | |
| SCHEMBL19936681 | 0.86 | FAAH (0.41) | EPHX1NAAAFAAHCASP2PLA2G2A | |
| SCHEMBL20903683 | 0.85 | EPHX1 (0.52) | EPHX1NAAAFAAHCASP2PLA2G2A | |
| SCHEMBL21527587 | 0.85 | EPHX1 (0.52) | EPHX1NAAAFAAHCASP2PLA2G2A | |
| SCHEMBL22447142 | 0.85 | EPHX1 (0.50) | EPHX1NAAAFAAHCASP2PLA2G2A | |
| SCHEMBL24041036 | 0.85 | EPHX1 (0.52) | EPHX1NAAAFAAHCASP2PLA2G2A | |
| SCHEMBL24133449 | 0.85 | EPHX1 (0.48) | EPHX1NAAAFAAHCASP2PLA2G2A | |
| SCHEMBL24133456 | 0.85 | EPHX1 (0.48) | EPHX1NAAAFAAHCASP2PLA2G2A | |
| SCHEMBL21076334 | 0.85 | EPHX1 (0.50) | EPHX1NAAAFAAHCASP2PLA2G2A | |
| SCHEMBL19336122 | 0.85 | EPHX1 (0.50) | EPHX1NAAAFAAHCASP2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858385-A2 | POLYMER-CONJUGATED METAP2 INHIBITORS, AND THERAPEUTIC METHODS OF USE THEREOF | Syndevrx, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |