Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | DPAGT1 | Q9H3H5 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24772633 | 1.00 | DUT (0.46) | DUTTDP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL21231206 | 0.95 | DUT (0.44) | DUTTDP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL21231208 | 0.95 | DUT (0.44) | DUTTDP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL20820789 | 0.95 | DUT (0.44) | DUTTDP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL19379558 | 0.95 | DUT (0.44) | DUTTDP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL19379550 | 0.95 | DUT (0.44) | DUTTDP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL23253968 | 0.95 | DUT (0.44) | DUTTDP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL23253969 | 0.95 | DUT (0.44) | DUTTDP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13253096 | 0.91 | DUT (0.44) | DUTTDP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL24059207 | 0.91 | DUT (0.44) | DUTTDP1SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220290145-A1 | Modified RNA Agents with Reduced Off-Target Effect | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-09-15 | — | — | US | disclosed |
| US-20210238595-A1 | MODIFIED RNA AGENTS WITH REDUCED OFF-TARGET EFFECT | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-08-05 | — | — | US | disclosed |