SCHEMBL24059207

SCHEMBL24059207

C[C@@H](O)[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C(F)C1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DUT P33316 3/20 0.44
TDP1 Q9NUW8 1/20 0.40
SLC28A1 O00337 1/20 0.38
SLC28A2 O43868 1/20 0.38
SLC29A1 Q99808 1/20 0.38
SLC28A3 Q9HAS3 1/20 0.38
P2RY14 Q15391 2/20 0.36
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
P2RY2 P41231 4/20 0.35
P2RY6 Q15077 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13253107 1.00 DUT (0.44) DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL13253096 1.00 DUT (0.44) DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL19379548 1.00 DUT (0.44) DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL24059089 1.00 DUT (0.44) DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL13253109 0.93 DUT (0.46) DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL23710668 0.91 DUT (0.46) DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL24772633 0.91 DUT (0.46) DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL20820789 0.88 DUT (0.44) DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL21231206 0.88 DUT (0.44) DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL21231208 0.88 DUT (0.44) DUTTDP1SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
WO-2021234459-A9 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2022-02-03 WO disclosed
WO-2021234459-A2 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2021-11-25 WO disclosed