SCHEMBL23711041

SCHEMBL23711041

O=C1CCC(N2Cc3cc(C4CCN(CCCCCCCNC5CCCCC5)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 16/20 0.61
▸ IKZF1 Q13422 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30619768 0.87 IKZF2 (0.70) IKZF2IKZF1
SCHEMBL23710930 0.86 IKZF2 (0.60) IKZF2IKZF1
SCHEMBL20774943 0.85 IKZF2 (0.75) IKZF2IKZF1
SCHEMBL23711044 0.85 IKZF2 (0.61) IKZF2IKZF1
SCHEMBL20765278 0.84 IKZF2 (0.76) IKZF2IKZF1
SCHEMBL30369147 0.84 IKZF2 (0.76) IKZF2IKZF1
SCHEMBL24790883 0.84 IKZF2 (0.72) IKZF2IKZF1
SCHEMBL20774914 0.84 IKZF2 (0.70) IKZF2IKZF1
SCHEMBL30368787 0.84 IKZF2 (0.70) IKZF2IKZF1
SCHEMBL30889707 0.83 IKZF2 (0.65) IKZF2IKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021155050-A1 KINASE MODULATORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX, INC. (US) 2021-08-05 — — WO disclosed
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