Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30556358 | 0.83 | CNR1 (0.42) | CNR1HRH4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23111898 | 0.83 | CNR1 (0.42) | CNR1HRH4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30556366 | 0.83 | CNR1 (0.42) | CNR1HRH4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23111896 | 0.83 | CNR1 (0.42) | CNR1HRH4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23712320 | 0.81 | HRH4 (0.54) | HRH4 | |
| SCHEMBL23712343 | 0.79 | GRIN1 (0.50) | HRH4EIF4A3MEN1KMT2A | |
| SCHEMBL23712332 | 0.79 | MLLT1 (0.49) | CNR1EIF4A3SLC2A1GHSRSETD2 | |
| SCHEMBL18183345 | 0.75 | CNR1 (0.48) | CNR1HRH4CYP2C19EIF4A3SLC2A1 | |
| SCHEMBL23712330 | 0.74 | HRH4 (0.55) | HRH4 | |
| SCHEMBL29655554 | 0.71 | CNR1 (0.46) | CNR1CYP2C19EIF4A3SLC2A1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718633-B2 | Indole compounds, process for the preparation and use thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2023-08-08 | — | — | US | disclosed |
| US-20210238204-A1 | INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718633-B2 | Indole compounds, process for the preparation and use thereof | IDO1, IDO2, INMT | CNR1 603/4885HRH4 1210/4885CYP2D6 147/4885 |
| US-20210238204-A1 | INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION AND USE THEREOF | IDO1, IDO2, INMT | CNR1 603/4885HRH4 1210/4885CYP2D6 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.