Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxirane SCHEMBL8660005 | 0.89 | TSHR (0.44) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9781051 | 0.87 | CYP4F2 (0.43) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL27963140 | 0.81 | HCAR2 (0.38) | ALDH1A1LMNAKDM4EATMTSHR | |
| SCHEMBL27345989 | 0.80 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL27912040 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAATML3MBTL1CYP1A2 | |
| SCHEMBL6487289 | 0.77 | DGAT1 (0.36) | ALDH1A1HSD17B10MGAMGAASI | |
| SCHEMBL27380366 | 0.77 | — | — | |
| SCHEMBL27963882 | 0.77 | — | — | |
| SCHEMBL28196215 | 0.76 | ALDH1A1 (0.44) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6488225 | 0.76 | TSHR (0.42) | ALDH1A1HSD17B10GAATHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101848905-A | Process for the enantioselective preparation of pregabalin | ESTEVE LABOR DR | 2010-09-29 | — | — | CN | claimed |
| CN-100469814-C | Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium | TORAY INDUSTRIES (JP) | 2009-03-18 | — | — | CN | claimed |
| CN-101287705-A | Synthesis of 1 alpha-fluoro-25-hydroxy-16-23E-diene-26, 27-bishomo-20-epi-cholecalciferol | BIOXELL SPA (IT) | 2008-10-15 | — | — | CN | claimed |
| CN-1703440-A | Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium | TORAY INDUSTRIES (JP) | 2005-11-30 | — | — | CN | claimed |
| JP-63277683-A | — | — | None | — | — | JP | disclosed |
| CN-105392777-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2020-09-22 | — | — | CN | disclosed |
| CN-107207472-B | Inhibitors of AKT kinase | 卑尔根生物股份公司 | 2020-08-14 | — | — | CN | disclosed |
| EP-3094626-B1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS RXR AGONISTS | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-02-19 | — | — | EP | disclosed |
| CN-106415910-B | Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2019-05-03 | — | — | CN | disclosed |
| CN-106232672-B | Masterbatch polymer blend | 东洋纺株式会社 | 2018-11-13 | — | — | CN | disclosed |
| CN-103917569-B | Polyurethane-base barrier film and/or spacer body for electrochemical cell | 路博润高级材料公司 | 2018-04-10 | — | — | CN | disclosed |
| US-9862713-B2 | Substituted bicyclic heteroaryl compounds as RXR agonists | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2018-01-09 | — | — | US | disclosed |
| CN-1042356-A | 1, 4-diaza * derivatives and their pharmaceutical use | EISAI CO LTD (JP) | 1990-05-23 | — | — | CN | disclosed |
| CN-1032786-A | N-acyl amino acid derivative and uses thereof | BANYU PHARMA CO LTD (JP) | 1989-05-10 | — | — | CN | disclosed |
| JP-S63277683-A | 5-THIABENZ(CD)INDOLE DERIVATIVE | SAGAMI CHEM RES CENTER | 1988-11-15 | — | — | JP | disclosed |
| US-4319048-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1982-03-09 | — | — | US | disclosed |
| US-4187247-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4163103-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4107190-A | ANTITUMOR | HOFFMANN-LA ROCHE INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4054589-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-10-18 | — | — | US | disclosed |