Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136447 | 0.83 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL13784537 | 0.77 | MAOB (0.47) | MAOBGFERMAPTHTR2AMAOA | |
| SCHEMBL111607 | 0.73 | GFER (0.62) | MAOBGFERMAPTHTR2AMAOA | |
| SCHEMBL8100042 | 0.72 | MAOB (0.55) | MAOBGFERMAPTHTR2AMAOA | |
| SCHEMBL8100323 | 0.72 | MAOB (0.50) | MAOBGFERMAPTHTR2AMAOA | |
| SCHEMBL11244317 | 0.72 | GFER (0.54) | MAOBGFERHTR2AMAOAALDH1A1 | |
| SCHEMBL109256 | 0.72 | HTR2A (0.72) | MAOBGFERMAPTHTR2AKDM4E | |
| Iodide SCHEMBL31425562 | 0.72 | HTR2A (0.59) | MAOBGFERMAPTHTR2AMAOA | |
| Hydrochloric Acid SCHEMBL2857384 | 0.72 | MAOB (0.61) | MAOBGFERMAPTHTR2AMAOA | |
| SCHEMBL10605113 | 0.72 | MAOB (0.48) | MAOBGFERMAPTHTR2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858835-A1 | PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS | G1 Therapeutics, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |