Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660732 | 0.88 | FTO (0.52) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL312455 | 0.87 | FTO (0.55) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL24943523 | 0.85 | FTO (0.48) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL20832 | 0.84 | ALDH1A1 (0.60) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL5275280 | 0.83 | HPGD (0.54) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL14359783 | 0.82 | FTO (0.46) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL4416360 | 0.82 | FTO (0.57) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL26795632 | 0.81 | ALB (0.46) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL6850491 | 0.81 | FTO (0.60) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL2932897 | 0.81 | FTO (0.54) | HPGDALDH1A1ALOX12CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2548024-A2 | ARSENICAL FLUORESCENT AGENTS AND ASSAYS | SRI International (US) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011116401-A9 | ARSENICAL FLUORESCENT AGENTS AND ASSAYS | SRI INTERNATIONAL (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2011116401-A2 | ARSENICAL FLUORESCENT AGENTS AND ASSAYS | SRI INTERNATIONAL (US) | 2011-09-22 | — | — | WO | disclosed |