Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400186 | 1.00 | NCF1 (0.37) | NCF1SLC6A3GNAI3GNAO1GNAI1 | |
| SCHEMBL22680846 | 1.00 | NCF1 (0.37) | NCF1SLC6A3GNAI3GNAO1GNAI1 | |
| SCHEMBL25091220 | 0.91 | NCF1 (0.39) | NCF1SLC6A3GNAI3GNAO1GNAI1 | |
| SCHEMBL19578758 | 0.90 | CACNA2D1 (0.34) | — | |
| SCHEMBL18470452 | 0.89 | NCF1 (0.38) | NCF1SLC6A3GNAI3GNAO1GNAI1 | |
| SCHEMBL21725570 | 0.88 | GNAI3 (0.43) | GNAI3GNAO1GNAI1 | |
| SCHEMBL25992171 | 0.88 | GNAI3 (0.43) | GNAI3GNAO1GNAI1 | |
| SCHEMBL19542241 | 0.88 | GNAI3 (0.43) | GNAI3GNAO1GNAI1 | |
| SCHEMBL21859550 | 0.84 | NCF1 (0.38) | NCF1SLC6A3 | |
| SCHEMBL14431980 | 0.84 | NCF1 (0.38) | NCF1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3594203-B1 | SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-08-04 | — | — | EP | disclosed |