Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 12/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PDE1A | P54750 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 12/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2371130 | 0.83 | PDE4A (0.60) | PDE4DPDE5APDE1APDE1BPDE1C | |
| SCHEMBL3238870 | 0.82 | PDE4A (0.44) | PDE4DPDE4APDE4BPDE4CFPR2 | |
| SCHEMBL3239769 | 0.82 | PDE4A (0.44) | PDE4DPDE4APDE4BPDE4CFPR2 | |
| SCHEMBL3262515 | 0.80 | PDE4B (0.45) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3224875 | 0.80 | PDE4A (0.50) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3262220 | 0.80 | PDE4A (0.50) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3227674 | 0.79 | PDE4A (0.44) | PDE4DPDE4APDE4BPDE4CFPR2 | |
| SCHEMBL3263111 | 0.79 | PDE4A (0.46) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3239630 | 0.79 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3262194 | 0.79 | PDE4A (0.60) | PDE4DPDE4APDE4BPDE4CFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114103-A1 | PYRIMIDINONES FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2011-09-22 | — | — | WO | disclosed |