Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.60 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2371431 | 0.83 | PDE4D (0.51) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL2371367 | 0.75 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL3260373 | 0.75 | PDE4A (0.80) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL3261887 | 0.73 | PDE4A (0.53) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL1157585 | 0.69 | PDE5A (0.54) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL5823060 | 0.68 | PDE4A (0.77) | PDE4APDE4DPDE4BPDE4CFPR2 | |
| SCHEMBL7448551 | 0.68 | PDE4A (0.62) | PDE4APDE4DPDE4BPDE4CFPR2 | |
| SCHEMBL7364691 | 0.67 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4CFPR2 | |
| SCHEMBL6919617 | 0.67 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4CFPR2 | |
| SCHEMBL6873641 | 0.67 | PDE4A (0.60) | PDE4APDE4DPDE4BPDE4CPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114103-A1 | PYRIMIDINONES FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2011-09-22 | — | — | WO | disclosed |