Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.31 |
| ▸ | RAC2 | P15153 | 1/20 | 0.31 |
| ▸ | RAC3 | P60763 | 1/20 | 0.31 |
| ▸ | CDC42 | P60953 | 1/20 | 0.31 |
| ▸ | RAC1 | P63000 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23252747 | 0.95 | KDM4E (0.38) | KDM4EATML3MBTL1TSPOHDAC4 | |
| SCHEMBL18544662 | 0.85 | KDM4E (0.32) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL29335662 | 0.84 | PTGER4 (0.38) | KDM4EATML3MBTL1HDAC4PTGER4 | |
| SCHEMBL20470859 | 0.84 | KDM4E (0.40) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL21532824 | 0.84 | KDM4E (0.43) | KDM4EATML3MBTL1TSPOHDAC4 | |
| SCHEMBL21881045 | 0.83 | HDAC4 (0.38) | KDM4EATML3MBTL1HDAC4PTGER4 | |
| SCHEMBL24900342 | 0.83 | KDM4E (0.36) | KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL26000317 | 0.83 | PTGER4 (0.36) | KDM4EATML3MBTL1HDAC4PTGER4 | |
| SCHEMBL24445328 | 0.83 | TSPO (0.30) | TSPO | |
| SCHEMBL23679232 | 0.82 | L3MBTL1 (0.41) | KDM4EATML3MBTL1TSPOHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858842-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2021-08-04 | — | — | EP | disclosed |