Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937860 | 0.81 | HPGD (0.63) | HPGDTSHRALDH1A1KMT2A | |
| SCHEMBL10210773 | 0.81 | HPGD (0.63) | HPGDTSHRALDH1A1KMT2AMAPT | |
| SCHEMBL4431567 | 0.79 | HPGD (0.66) | HPGDTSHRALDH1A1KDM4EMAPT | |
| SCHEMBL6738518 | 0.79 | TSHR (0.96) | HPGDTSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL9612077 | 0.78 | TSHR (1.00) | HPGDTSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL3936704 | 0.78 | TSHR (1.00) | HPGDTSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL10169498 | 0.77 | HPGD (0.58) | HPGDTSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL14050542 | 0.77 | HPGD (0.62) | HPGDTSHRALDH1A1KDM4EMAPT | |
| SCHEMBL8532609 | 0.75 | ENPP2 (0.54) | TSHRALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL7929101 | 0.75 | ENPP2 (0.54) | ALDH1A1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3594203-B1 | SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-08-04 | — | — | EP | disclosed |