⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23714730 | 0.80 | ADH1B (0.32) | — | |
| SCHEMBL24159302 | 0.69 | — | — | |
| SCHEMBL23714734 | 0.65 | — | — | |
| SCHEMBL23714729 | 0.61 | — | — | |
| SCHEMBL23570969 | 0.56 | IDO1 (0.39) | — | |
| SCHEMBL24981316 | 0.55 | — | — | |
| SCHEMBL17776558 | 0.55 | — | — | |
| SCHEMBL23765466 | 0.55 | — | — | |
| SCHEMBL24158818 | 0.55 | ADH1B (0.31) | — | |
| Hydrochloric Acid SCHEMBL29946735 | 0.54 | MDM2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155320-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |