SCHEMBL23714730

SCHEMBL23714730

COC(=N)/C(=C\NC1CCC1)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH7 P40394 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23714733 0.80
SCHEMBL24159302 0.71
SCHEMBL19992504 0.68 ADH1B (0.38) ADH1BADH1CADH1AADH7
SCHEMBL24014855 0.66 ADH1B (0.39) ADH1BADH1CADH1AADH7
SCHEMBL22702026 0.64 ADH1B (0.38) ADH1BADH1CADH1AADH7
SCHEMBL24158818 0.64 ADH1B (0.31) ADH1BADH1A
SCHEMBL23714734 0.63
SCHEMBL23422610 0.62 ADH1B (0.39) ADH1BADH1CADH1AADH7
SCHEMBL29338660 0.62 ADH1B (0.35) ADH1BADH1CADH1AADH7
SCHEMBL25948773 0.61 ADH1B (0.31) ADH1BADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021155320-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2021-08-05 WO disclosed