Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30041544 | 0.86 | CA12 (0.38) | RARARARBRARGRXRARXRB | |
| SCHEMBL30041233 | 0.86 | CA12 (0.38) | RARARARBRARGRXRARXRB | |
| SCHEMBL31396120 | 0.86 | CA12 (0.38) | RARARARBRARGRXRARXRB | |
| SCHEMBL23704795 | 0.86 | CA12 (0.38) | RARARARBRARGRXRARXRB | |
| SCHEMBL31396317 | 0.86 | CA12 (0.38) | RARARARBRARGRXRARXRB | |
| SCHEMBL23705080 | 0.86 | CA12 (0.38) | RARARARBRARGRXRARXRB | |
| SCHEMBL23706097 | 0.86 | CA12 (0.38) | RARARARBRARGRXRARXRB | |
| SCHEMBL23714588 | 0.83 | NPC1 (0.41) | RARARARBRARG | |
| SCHEMBL30041183 | 0.82 | KDM1A (0.38) | — | |
| SCHEMBL23714665 | 0.78 | OPRM1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155320-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |